Mouse models of myeloproliferative neoplasms: JAK of all grades
In 2005, several groups identified a single gain-of-function point mutation in the JAK2 kinase that was present in the majority of patients with myeloproliferative neoplasms (MPNs). Since this discovery, much effort has been dedicated to understanding the molecular consequences of the JAK2V617F muta...
| Main Authors: | , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
The Company of Biologists Limited
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097453/ |