Chromatin remodelling complex dosage modulates transcription factor function in heart development

Dominant mutations in cardiac transcription factor genes cause human inherited congenital heart defects (CHDs); however, their molecular basis is not understood. Interactions between transcription factors and the Brg1/Brm-associated factor (BAF) chromatin remodelling complex suggest potential mechan...

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Bibliographic Details
Main Authors: Takeuchi, Jun K., Lou, Xin, Alexander, Jeffrey M., Sugizaki, Hiroe, Delgado-OlguĂ­n, Paul, Holloway, Alisha K., Mori, Alessandro D., Wylie, John N., Munson, Chantilly, Zhu, Yonghong, Zhou, Yu-Qing, Yeh, Ru-Fang, Henkelman, R. Mark, Harvey, Richard P., Metzger, Daniel, Chambon, Pierre, Stainier, Didier Y. R., Pollard, Katherine S., Scott, Ian C., Bruneau, Benoit G.
Format: Online
Language:English
Published: Nature Publishing Group 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096875/