A novel tumor suppressor function for the Notch pathway in myeloid leukemia

A novel tumor suppressor function for the Notch pathway in myeloid leukemia

Notch signaling is a central regulator of differentiation in a variety of organisms and tissue types1. Its activity is controlled by the multi-subunit γ–secretase complex (γSE) complex2. Although Notch signaling can play both oncogenic and tumor suppressor roles in solid tumors, in the hematopoietic...

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Bibliographic Details
Main Authors: Klinakis, Apostolos, Lobry, Camille, Abdel-Wahab, Omar, Oh, Philmo, Haeno, Hiroshi, Buonamici, Silvia, van De Walle, Inge, Cathelin, Severine, Trimarchi, Thomas, Araldi, Elisa, Liu, Cynthia, Ibrahim, Sherif, Beran, Miroslav, Zavadil, Jiri, Efstratiadis, Argiris, Taghon, Tom, Michor, Franziska, Levine, Ross L., Aifantis, Iannis
Format: Online
Language:English
Published: 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093658/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093658/

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