Critical role for Gimap5 in the survival of mouse hematopoietic stem and progenitor cells

HSCs lacking the guanosine nucleotide-binding protein Gimap5, which stabilizes expression of the Mcl-1 Bcl2 family protein, exhibit impaired survival and long-term repopulation capacity.

Bibliographic Details
Main Authors: Chen, Yuhong, Yu, Mei, Dai, Xuezhi, Zogg, Mark, Wen, Renren, Weiler, Hartmut, Wang, Demin
Format: Online
Language:English
Published: The Rockefeller University Press 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092340/