Mycobacterium marinum MMAR_2380, a predicted transmembrane acyltransferase, is essential for the presence of the mannose cap on lipoarabinomannan

Lipoarabinomannan (LAM) is a major glycolipid in the mycobacterial cell envelope. LAM consists of a mannosylphosphatidylinositol (MPI) anchor, a mannan core and a branched arabinan domain. The termini of the arabinan branches can become substituted with one to three α(1→2)-linked mannosyl residues,...

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Main Authors: Driessen, Nicole N., Stoop, Esther J. M., Ummels, Roy, Gurcha, Sudagur S., Mishra, Arun K., Larrouy-Maumus, Gérald, Nigou, Jérôme, Gilleron, Martine, Puzo, Germain, Maaskant, Janneke J., Sparrius, Marion, Besra, Gurdyal S., Bitter, Wilbert, Vandenbroucke-Grauls, Christina M. J. E., Appelmelk, Ben J.
Format: Online
Language:English
Published: Society for General Microbiology 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090144/