Specificity of Mimotope-Induced Anti-High Molecular Weight-Melanoma Associated Antigen (HMW-MAA) Antibodies Does Not Ensure Biological Activity

Vaccines based on peptide mimics (mimotopes) of conformational tumor antigen epitopes have been investigated for a variety of human tumors including breast cancer, tumors expressing the carcinoembryonic antigen, B cell lymphoma, neuroblastoma, and melanoma. In our previous work, we designed a vaccin...

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Bibliographic Details
Main Authors: Latzka, Julia, Gaier, Sonja, Hofstetter, Gerlinde, Balazs, Nina, Smole, Ursula, Ferrone, Soldano, Scheiner, Otto, Breiteneder, Heimo, Pehamberger, Hubert, Wagner, Stefan
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089623/