Temporal Profiling of Orexin Receptor-Arrestin-Ubiquitin Complexes Reveals Differences between Receptor Subtypes*

Orexin G protein-coupled receptors (OxRs) and their cognate agonists have been implicated in a number of disorders since their recent discovery, ranging from narcolepsy to formation of addictive behavior. Bioluminescence resonance energy transfer assays of agonist-occupied OxRs provided evidence for...

Full description

Bibliographic Details
Main Authors: Dalrymple, Matthew B., Jaeger, Werner C., Eidne, Karin A., Pfleger, Kevin D. G.
Format: Online
Language:English
Published: American Society for Biochemistry and Molecular Biology 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089514/