Temporal Profiling of Orexin Receptor-Arrestin-Ubiquitin Complexes Reveals Differences between Receptor Subtypes*
Orexin G protein-coupled receptors (OxRs) and their cognate agonists have been implicated in a number of disorders since their recent discovery, ranging from narcolepsy to formation of addictive behavior. Bioluminescence resonance energy transfer assays of agonist-occupied OxRs provided evidence for...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
American Society for Biochemistry and Molecular Biology
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089514/ |