CPEB and two poly(A) polymerases control miR-122 stability and p53 mRNA translation

Cytoplasmic polyadenylation-induced translation controls germ cell development1,2, neuronal synaptic plasticity3-5, and cellular senescence6,7, a tumor-suppressor mechanism that limits the replicative lifespan of cells8,9 . The cytoplasmic polyadenylation element binding protein (CPEB) promotes poly...

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Bibliographic Details
Main Authors: Burns, David, D'Ambrogio, Andrea, Nottrott, Stephanie, Richter, Joel D.
Format: Online
Language:English
Published: 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3088779/