Suppression of Lung Adenocarcinoma Progression by Nkx2-1

Despite the high prevalence and poor outcome of patients with metastatic lung cancer, the mechanisms of tumour progression and metastasis remain largely uncharacterized. We modelled human lung adenocarcinoma, which frequently harbours activating point mutations in KRAS1 and inactivation of the p53-p...

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Bibliographic Details
Main Authors: Winslow, Monte M., Dayton, Talya L., Verhaak, Roel G. W., Kim-Kiselak, Caroline, Snyder, Eric L., Feldser, David M., Hubbard, Diana D., DuPage, Michel J., Whittaker, Charles A., Hoersch, Sebastian, Yoon, Stephanie, Crowley, Denise, Bronson, Roderick T., Chiang, Derek Y., Meyerson, Matthew, Jacks, Tyler
Format: Online
Language:English
Published: 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3088778/