Method for comparing visual field defects to local RNFL and RGC damage seen on frequency domain OCT in patients with glaucoma.

To relate structural (anatomical) and functional (behavioral) measures of glaucomatous damage, a method is described for comparing visual field defects to local retinal ganglion cell (RGC) and retinal nerve fiber layer (RNFL) thicknesses. Thickness maps of the RNFL and the RGC + inner plexiform laye...

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Main Authors: Hood, Donald C., Raza, Ali S.
Format: Online
Language:English
Published: Optical Society of America 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087567/
id pubmed-3087567
recordtype oai_dc
spelling pubmed-30875672011-05-10 Method for comparing visual field defects to local RNFL and RGC damage seen on frequency domain OCT in patients with glaucoma. Hood, Donald C. Raza, Ali S. Ophthalmology Applications To relate structural (anatomical) and functional (behavioral) measures of glaucomatous damage, a method is described for comparing visual field defects to local retinal ganglion cell (RGC) and retinal nerve fiber layer (RNFL) thicknesses. Thickness maps of the RNFL and the RGC + inner plexiform layer, obtained with frequency domain optical coherence tomography (fdOCT), were transformed into probability maps by comparing them to a normative group. As demonstrated in patients with glaucomatous damage to the macula, the probability map associated with the patient’s visual field can be directly compared to the fdOCT probability maps by taking into consideration the displacement of the RGCs. Optical Society of America 2011-04-05 /pmc/articles/PMC3087567/ /pubmed/21559122 http://dx.doi.org/10.1364/BOE.2.001097 Text en ©2011 Optical Society of America http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported License, which permits download and redistribution, provided that the original work is properly cited. This license restricts the article from being modified or used commercially.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Hood, Donald C.
Raza, Ali S.
spellingShingle Hood, Donald C.
Raza, Ali S.
Method for comparing visual field defects to local RNFL and RGC damage seen on frequency domain OCT in patients with glaucoma.
author_facet Hood, Donald C.
Raza, Ali S.
author_sort Hood, Donald C.
title Method for comparing visual field defects to local RNFL and RGC damage seen on frequency domain OCT in patients with glaucoma.
title_short Method for comparing visual field defects to local RNFL and RGC damage seen on frequency domain OCT in patients with glaucoma.
title_full Method for comparing visual field defects to local RNFL and RGC damage seen on frequency domain OCT in patients with glaucoma.
title_fullStr Method for comparing visual field defects to local RNFL and RGC damage seen on frequency domain OCT in patients with glaucoma.
title_full_unstemmed Method for comparing visual field defects to local RNFL and RGC damage seen on frequency domain OCT in patients with glaucoma.
title_sort method for comparing visual field defects to local rnfl and rgc damage seen on frequency domain oct in patients with glaucoma.
description To relate structural (anatomical) and functional (behavioral) measures of glaucomatous damage, a method is described for comparing visual field defects to local retinal ganglion cell (RGC) and retinal nerve fiber layer (RNFL) thicknesses. Thickness maps of the RNFL and the RGC + inner plexiform layer, obtained with frequency domain optical coherence tomography (fdOCT), were transformed into probability maps by comparing them to a normative group. As demonstrated in patients with glaucomatous damage to the macula, the probability map associated with the patient’s visual field can be directly compared to the fdOCT probability maps by taking into consideration the displacement of the RGCs.
publisher Optical Society of America
publishDate 2011
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087567/
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