Impacts of Membrane Biophysics in Alzheimer's Disease: From Amyloid Precursor Protein Processing to Aβ Peptide-Induced Membrane Changes
An increasing amount of evidence supports the notion that cytotoxic effects of amyloid-β peptide (Aβ), the main constituent of senile plaques in Alzheimer's disease (AD), are strongly associated with its ability to interact with membranes of neurons and other cerebral cells. Aβ is derived from...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
SAGE-Hindawi Access to Research
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087431/ |