Systemically Administered Ligands of Toll-Like Receptor 2, -4, and -9 Induce Distinct Inflammatory Responses in the Murine Lung

Systemically Administered Ligands of Toll-Like Receptor 2, -4, and -9 Induce Distinct Inflammatory Responses in the Murine Lung

Objective. To determine whether systemically administered TLR ligands differentially modulate pulmonary inflammation. Methods. Equipotent doses of LPS (20 mg/kg), CpG-ODN (1668-thioat 1 nmol/g), or LTA (15 mg/kg) were determined via TNF activity assay. C57BL/6 mice were challenged intraperitoneall...

Full description

Bibliographic Details
Main Authors: Ehrentraut, H., Meyer, R., Schwederski, M., Ehrentraut, S., Velten, M., Grohé, C., Knuefermann, P., Baumgarten, G., Boehm, O.
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086362/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086362/

Similar Items