Sema3E/Plexin-D1 Mediated Epithelial-to-Mesenchymal Transition in Ovarian Endometrioid Cancer

Cancer cells often employ developmental cues for advantageous growth and metastasis. Here, we report that an axon guidance molecule, Sema3E, is highly expressed in human high-grade ovarian endometrioid carcinoma, but not low-grade or other ovarian epithelial tumors, and facilitates tumor progression...

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Bibliographic Details
Main Authors: Tseng, Chun-Hsien, Murray, Karl D., Jou, Mu-Fan, Hsu, Su-Ming, Cheng, Hwai-Jong, Huang, Pei-Hsin
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084850/