Completion of Hepatitis C Virus Replication Cycle in Heterokaryons Excludes Dominant Restrictions in Human Non-liver and Mouse Liver Cell Lines

Completion of Hepatitis C Virus Replication Cycle in Heterokaryons Excludes Dominant Restrictions in Human Non-liver and Mouse Liver Cell Lines

Hepatitis C virus (HCV) is hepatotropic and only infects humans and chimpanzees. Consequently, an immunocompetent small animal model is lacking. The restricted tropism of HCV likely reflects specific host factor requirements. We investigated if dominant restriction factors expressed in non-liver or...

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Bibliographic Details
Main Authors: Frentzen, Anne, Hüging, Kathrin, Bitzegeio, Julia, Friesland, Martina, Haid, Sibylle, Gentzsch, Juliane, Hoffmann, Markus, Lindemann, Dirk, Zimmer, Gert, Zielecki, Florian, Weber, Friedemann, Steinmann, Eike, Pietschmann, Thomas
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084199/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084199/

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