Epigenetic Inactivation of the miR-124-1 in Haematological Malignancies

Epigenetic Inactivation of the miR-124-1 in Haematological Malignancies

miR-124-1 is a tumour suppressor microRNA (miR). Epigenetic deregulation of miRs is implicated in carcinogenesis. Promoter DNA methylation and histone modification of miR-124-1 was studied in 5 normal marrow controls, 4 lymphoma, 8 multiple myeloma (MM) cell lines, 230 diagnostic primary samples of...

Full description

Bibliographic Details
Main Authors: Wong, Kwan Yeung, So, Chi Chiu, Loong, Florence, Chung, Lap Ping, Lam, William Wai Lung, Liang, Raymond, Li, George Kam Hop, Jin, Dong-Yan, Chim, Chor Sang
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081325/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081325/

Similar Items