Network Archaeology: Uncovering Ancient Networks from Present-Day Interactions

What proteins interacted in a long-extinct ancestor of yeast? How have different members of a protein complex assembled together over time? Our ability to answer such questions has been limited by the unavailability of ancestral protein-protein interaction (PPI) networks. To overcome this limitation...

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Bibliographic Details
Main Authors: Navlakha, Saket, Kingsford, Carl
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077358/