The BRAFV600E mutation: what is it really orchestrating in thyroid cancer?
BRAFV600E is a constitutively active onco-kinase and is the most common genetic alteration in papillary thyroid carcinoma (PTC), and in anaplastic thyroid carcinoma as well, albeit at a lower frequency. The BRAFV600E mutation in some studies has been significantly associated with extra-thyroidal ext...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Impact Journals LLC
2010
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074562/ |