Naked1 Antagonizes Wnt Signaling by Preventing Nuclear Accumulation of β-Catenin

Naked1 Antagonizes Wnt Signaling by Preventing Nuclear Accumulation of β-Catenin

Cyto-nuclear shuttling of β-catenin is at the epicenter of the canonical Wnt pathway and mutations in genes that result in excessive nuclear accumulation of β-catenin are the driving force behind the initiation of many cancers. Recently, Naked Cuticle homolog 1 (Nkd1) has been identified as a Wnt-in...

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Bibliographic Details
Main Authors: Van Raay, Terence J., Fortino, Nicholas J., Miller, Bryan W., Ma, Haiting, Lau, Garnet, Li, Cunxi, Franklin, Jeffery L., Attisano, Liliana, Solnica-Krezel, Lilianna, Coffey, Robert J.
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072412/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072412/

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