Circadian Abnormalities in Motor Activity in a BAC Transgenic Mouse Model of Huntington’s Disease

Huntington’s disease (HD) is a progressive neurodegenerative disease marked by psychiatric and motor problems. Recently, these findings have been extended to deficits in sleep and circadian function that can be observed in HD patients and in HD mouse models, with abnormal sleep patterns correlating...

Full description

Bibliographic Details
Main Authors: Oakeshott, Stephen, Balci, Fuat, Filippov, Igor, Murphy, Carol, Port, Russell, Connor, David, Paintdakhi, Ahmad, LeSauter, Joseph, Menalled, Liliana, Ramboz, Sylvie, Kwak, Seung, Howland, David, Silver, Rae, Brunner, Dani
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072044/