The Driving Force of the Na+/Ca2+-Exchanger during Metabolic Inhibition

Objective: Metabolic inhibition causes a decline in mechanical performance and, if prolonged, myocardial contracture and cell death. The decline in mechanical performance is mainly due to altered intracellular calcium handling, which is under control of the Na+/Ca2+-exchanger (NCX) The driving force...

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Bibliographic Details
Main Authors: Baartscheer, Antonius, Schumacher, Cees A., Coronel, Ruben, Fiolet, Jan W. T.
Format: Online
Language:English
Published: Frontiers Research Foundation 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070476/