Relationship between Prion Propensity and the Rates of Individual Molecular Steps of Fibril Assembly*
Peptides and proteins possess an inherent propensity to self-assemble into generic fibrillar nanostructures known as amyloid fibrils, some of which are involved in medical conditions such as Alzheimer disease. In certain cases, such structures can self-propagate in living systems as prions and trans...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
American Society for Biochemistry and Molecular Biology
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069414/ |