Characterization of the transcriptional regulator Rv3124 of Mycobacterium tuberculosis identifies it as a positive regulator of molybdopterin biosynthesis and defines the functional consequences of a non-synonymous SNP in the Mycobacterium bovis BCG orthologue

Characterization of the transcriptional regulator Rv3124 of Mycobacterium tuberculosis identifies it as a positive regulator of molybdopterin biosynthesis and defines the functional consequences of a non-synonymous SNP in the Mycobacterium bovis BCG orthologue

A number of single-nucleotide polymorphisms (SNPs) have been identified in the genome of Mycobacterium bovis BCG Pasteur compared with the sequenced strain M. bovis 2122/97. The functional consequences of many of these mutations remain to be described; however, mutations in genes encoding regulators...

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Bibliographic Details
Main Authors: Mendoza Lopez, Pablo, Golby, Paul, Wooff, Esen, Garcia, Javier Nunez, Garcia Pelayo, M. Carmen, Conlon, Kevin, Gema Camacho, Ana, Hewinson, R. Glyn, Polaina, Julio, Suárez García, Antonio, Gordon, Stephen V.
Format: Online
Language:English
Published: Society for General Microbiology 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068679/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068679/

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