PtdIns 3-Kinase Orchestrates Autophagosome Formation in Yeast

Eukaryotic cells can massively transport their own cytoplasmic contents into a lytic compartment, the vacuole/lysosome, for recycling through a conserved system called autophagy. The key process in autophagy is the sequestration of cytoplasmic contents within a double-membrane structure, the autopha...

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Bibliographic Details
Main Authors: Obara, Keisuke, Ohsumi, Yoshinori
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3067060/