Preparation and evaluation of ofloxacin-loaded palmitic acid solid lipid nanoparticles

The purpose of this study was to use solid lipid nanoparticles (SLN) to improve the pharmacological activity of ofloxacin. Ofloxacin-loaded SLN were prepared using palmitic acid as lipid matrix and poly vinyl alcohol (PVA) as emulsifier by a hot homogenization and ultrasonication method. The physico...

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Bibliographic Details
Main Authors: Xie, Shuyu, Zhu, Luyan, Dong, Zhao, Wang, Yan, Wang, Xiaofang, Zhou, WenZhong
Format: Online
Language:English
Published: Dove Medical Press 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065800/