Cutaneous Squamous Cell Carcinoma of the Head and Neck
Cutaneous squamous cell carcinoma of the head and neck is an epidemic that reaches all parts of the world. Making the diagnosis relies on the acumen of the clinician and pathologist. Various pathologic subtypes exist and differ in histology and prognosis. High-risk tumors need aggressive treatment a...
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| Format: | Online |
| Language: | English |
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Hindawi Publishing Corporation
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064996/ |
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pubmed-30649962011-03-31 Cutaneous Squamous Cell Carcinoma of the Head and Neck Gurudutt, Vivek V. Genden, Eric M. Review Article Cutaneous squamous cell carcinoma of the head and neck is an epidemic that reaches all parts of the world. Making the diagnosis relies on the acumen of the clinician and pathologist. Various pathologic subtypes exist and differ in histology and prognosis. High-risk tumors need aggressive treatment and vigilant surveillance to monitor for recurrence. Large tumors, deep tissue invasion, perineural involvement, recurrence, location in high-risk areas, and immunosuppression are implicated in worsening prognosis. Surgery is the mainstay of treatment with adjuvant radiation therapy as needed for aggressive tumors; however, other modalities are potentially useful for low-risk lesions. The use of Mohs surgery has become increasingly useful and has shown high success rates. Involvement of parotid and neck lymph nodes significantly affects outcomes and the physician should be comfortable with management of this complex disease. This paper examines the diagnosis, pathology, clinical course, and treatment options for cutaneous squamous cell carcinoma of the head and neck. Hindawi Publishing Corporation 2011 2011-02-21 /pmc/articles/PMC3064996/ /pubmed/21461387 http://dx.doi.org/10.1155/2011/502723 Text en Copyright © 2011 V. V. Gurudutt and E. M. Genden. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Gurudutt, Vivek V. Genden, Eric M. |
| spellingShingle |
Gurudutt, Vivek V. Genden, Eric M. Cutaneous Squamous Cell Carcinoma of the Head and Neck |
| author_facet |
Gurudutt, Vivek V. Genden, Eric M. |
| author_sort |
Gurudutt, Vivek V. |
| title |
Cutaneous Squamous Cell Carcinoma of the Head and Neck |
| title_short |
Cutaneous Squamous Cell Carcinoma of the Head and Neck |
| title_full |
Cutaneous Squamous Cell Carcinoma of the Head and Neck |
| title_fullStr |
Cutaneous Squamous Cell Carcinoma of the Head and Neck |
| title_full_unstemmed |
Cutaneous Squamous Cell Carcinoma of the Head and Neck |
| title_sort |
cutaneous squamous cell carcinoma of the head and neck |
| description |
Cutaneous squamous cell carcinoma of the head and neck is an epidemic that reaches all parts of the world. Making the diagnosis relies on the acumen of the clinician and pathologist. Various pathologic subtypes exist and differ in histology and prognosis. High-risk tumors need aggressive treatment and vigilant surveillance to monitor for recurrence. Large tumors, deep tissue invasion, perineural involvement, recurrence, location in high-risk areas, and immunosuppression are implicated in worsening prognosis. Surgery is the mainstay of treatment with adjuvant radiation therapy as needed for aggressive tumors; however, other modalities are potentially useful for low-risk lesions. The use of Mohs surgery has become increasingly useful and has shown high success rates. Involvement of parotid and neck lymph nodes significantly affects outcomes and the physician should be comfortable with management of this complex disease. This paper examines the diagnosis, pathology, clinical course, and treatment options for cutaneous squamous cell carcinoma of the head and neck. |
| publisher |
Hindawi Publishing Corporation |
| publishDate |
2011 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064996/ |
| _version_ |
1611447134278647808 |