Antigen-Antibody docking reveals the molecular basis for cross-reactivity of the 1918 and 2009 Influenza A/H1N1 pandemic viruses

To understand the reported cross-reactivity of the 2009 H1N1 and the 1918 H1N1 pandemic viruses we docked the crystal structure of 2D1, an antibody derived from a survivor of the 1918 pandemic, to the structures of hemaglutinin (HA) of the 2009 strain and seasonal H1 vaccine strains. Our studies rev...

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Bibliographic Details
Main Authors: Cherian, Sarah, hil, Pratip, Mishra, Akhilesh Chandra
Format: Online
Language:English
Published: Biomedical Informatics 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064850/