The sodium-dependent di- and tricarboxylate transporter, NaCT, is not responsible for the uptake of D-, L-2-hydroxyglutarate and 3-hydroxyglutarate into neurons
Concentrations of glutarate (GA) and its derivatives such as 3-hydroxyglutarate (3OHGA), D- (D-2OHGA) and L-2-hydroxyglutarate (L-2OHGA) are increased in plasma, cerebrospinal fluid (CSF) and urine of patients suffering from different forms of organic acidurias. It has been proposed that these deriv...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
Springer Netherlands
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063566/ |