Human CD14dim Monocytes Patrol and Sense Nucleic Acids and Viruses via TLR7 and TLR8 Receptors

Human CD14dim Monocytes Patrol and Sense Nucleic Acids and Viruses via TLR7 and TLR8 Receptors

Monocytes are effectors of the inflammatory response to microbes. Human CD14+ monocytes specialize in phagocytosis and production of reactive oxygen species and secrete inflammatory cytokines in response to a broad range of microbial cues. Here, we have characterized the functions of human monocytes...

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Bibliographic Details
Main Authors: Cros, Jérôme, Cagnard, Nicolas, Woollard, Kevin, Patey, Natacha, Zhang, Shen-Ying, Senechal, Brigitte, Puel, Anne, Biswas, Subhra K., Moshous, Despina, Picard, Capucine, Jais, Jean-Philippe, D'Cruz, David, Casanova, Jean-Laurent, Trouillet, Céline, Geissmann, Fréderic
Format: Online
Language:English
Published: Cell Press 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063338/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063338/

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