Rh-Catalyzed rearrangement of vinylcyclopropane to 1,3-diene units attached to N-heterocycles
Dienes embedded in quinolizidine and indolizidine structures can be prepared in four steps from cyclic nitrones and bicyclopropylidene. The key intermediates α-spirocyclopropanated N-heterocyclic ketones, generated via a domino 1,3-dipolar cycloaddition/thermal rearrangement sequence, were converted...
| Main Authors: | , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Beilstein-Institut
2011
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063054/ |