Dendritic Cells and Hepatocytes Use Distinct Pathways to Process Protective Antigen from Plasmodium in vivo

Dendritic Cells and Hepatocytes Use Distinct Pathways to Process Protective Antigen from Plasmodium in vivo

Malaria-protective CD8+ T cells specific for the circumsporozoite (CS) protein are primed by dendritic cells (DCs) after sporozoite injection by infected mosquitoes. The primed cells then eliminate parasite liver stages after recognizing the CS epitopes presented by hepatocytes. To define the in viv...

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Bibliographic Details
Main Authors: Cockburn, Ian A., Tse, Sze-Wah, Radtke, Andrea J., Srinivasan, Prakash, Chen, Yun-Chi, Sinnis, Photini, Zavala, Fidel
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060173/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060173/

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