Structure of a bacterial ribonuclease P holoenzyme in complex with tRNA
Ribonuclease (RNase) P is the universal ribozyme responsible for 5′-end tRNA processing. We report the crystal structure of the Thermotoga maritima RNase P holoenzyme in complex with tRNAPhe. The 154 kDa complex consists of a large catalytic RNA (P RNA), a small protein cofactor, and mature tRNA. Th...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
2010
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058908/ |