The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance

The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance

Adult mouse LSK cells unable to undergo autophagy contain fewer HSCs, accumulate mitochondria, and fail to reconstitute lethally irradiated mice.

Bibliographic Details
Main Authors: Mortensen, Monika, Soilleux, Elizabeth J., Djordjevic, Gordana, Tripp, Rebecca, Lutteropp, Michael, Sadighi-Akha, Elham, Stranks, Amanda J., Glanville, Julie, Knight, Samantha, W. Jacobsen, Sten-Eirik, Kranc, Kamil R., Simon, Anna Katharina
Format: Online
Language:English
Published: The Rockefeller University Press 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058574/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058574/

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