A novel Minimalist Cell-Free MHC Class II Antigen Processing System Identifies Immunodominant Epitopes

A novel Minimalist Cell-Free MHC Class II Antigen Processing System Identifies Immunodominant Epitopes

Immunodominance is defined as restricted responsiveness of T cells to a few selected epitopes from complex antigens. Strategies currently used for elucidating CD4+ T cell epitopes are inadequate. To understand the mechanism of epitope selection for helper T cells, we established a cell-free antigen...

Full description

Bibliographic Details
Main Authors: Hartman, Isamu Z., Kim, AeRyon, Cotter, Robert J., Walter, Kimberly, Dalai, Sarat K., Boronina, Tatiana, Griffith, Wendell, Schwenk, Robert, Lanar, David E., Krzych, Urszula, Cole, Robert N., Sadegh-Nasseri, Scheherazade
Format: Online
Language:English
Published: 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058316/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058316/

Similar Items