Cannabinoid system and cyclooxygenases inhibitors

Cannabinoid system and cyclooxygenases inhibitors

Rationale. The cannabinoid system consists of a complex array of receptors, substances with agonist/antagonist properties for those receptors, biosynthetic machineries and mechanisms for cellular uptake and degradation for endocannabinoids. This system is in interrelation with other systems that com...

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Main Authors: Păunescu, H, Coman, OA, Coman, L, Ghiţă, I, Georgescu, SR, Drăia, F, Fulga, I
Format: Online
Language:English
Published: Carol Davila University Press 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056416/
id pubmed-3056416
recordtype oai_dc
spelling pubmed-30564162011-04-20 Cannabinoid system and cyclooxygenases inhibitors Păunescu, H Coman, OA Coman, L Ghiţă, I Georgescu, SR Drăia, F Fulga, I Review Rationale. The cannabinoid system consists of a complex array of receptors, substances with agonist/antagonist properties for those receptors, biosynthetic machineries and mechanisms for cellular uptake and degradation for endocannabinoids. This system is in interrelation with other systems that comprise lipid mediators like prostaglandins/leukotrienes systems. A clear antagonist, additive or synergic effect of nonsteroidal anti–inflammatory drugs (NSAIDs)–cannabinoid associations was not yet demonstrated. Aim. The present study tried to summarize the existent data on NSAIDS-cannabinoid system interactions. Carol Davila University Press 2011-02-15 2011-02-25 /pmc/articles/PMC3056416/ /pubmed/21505570 Text en ©Carol Davila University Press http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Păunescu, H
Coman, OA
Coman, L
Ghiţă, I
Georgescu, SR
Drăia, F
Fulga, I
spellingShingle Păunescu, H
Coman, OA
Coman, L
Ghiţă, I
Georgescu, SR
Drăia, F
Fulga, I
Cannabinoid system and cyclooxygenases inhibitors
author_facet Păunescu, H
Coman, OA
Coman, L
Ghiţă, I
Georgescu, SR
Drăia, F
Fulga, I
author_sort Păunescu, H
title Cannabinoid system and cyclooxygenases inhibitors
title_short Cannabinoid system and cyclooxygenases inhibitors
title_full Cannabinoid system and cyclooxygenases inhibitors
title_fullStr Cannabinoid system and cyclooxygenases inhibitors
title_full_unstemmed Cannabinoid system and cyclooxygenases inhibitors
title_sort cannabinoid system and cyclooxygenases inhibitors
description Rationale. The cannabinoid system consists of a complex array of receptors, substances with agonist/antagonist properties for those receptors, biosynthetic machineries and mechanisms for cellular uptake and degradation for endocannabinoids. This system is in interrelation with other systems that comprise lipid mediators like prostaglandins/leukotrienes systems. A clear antagonist, additive or synergic effect of nonsteroidal anti–inflammatory drugs (NSAIDs)–cannabinoid associations was not yet demonstrated. Aim. The present study tried to summarize the existent data on NSAIDS-cannabinoid system interactions.
publisher Carol Davila University Press
publishDate 2011
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056416/
_version_ 1611445358831861760

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