Interleukin-1beta induces MUC2 gene expression and mucin secretion via activation of PKC-MEK/ERK, and PI3K in human airway epithelial cells.

Interleukin-1beta induces MUC2 gene expression and mucin secretion via activation of PKC-MEK/ERK, and PI3K in human airway epithelial cells.

Interleukin 1beta(IL-1beta), a proinflammatory cytokine, is related with inflammatory diseases and it up-regulates MUC2 gene expression and mucin secretion. This study was designed to investigate the signal transduction pathway of the IL-1beta-mediated MUC2 gene expression and mucin secretion in hum...

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Bibliographic Details
Main Authors: Kim, Yong-Dae, Jeon, Jae-Yun, Woo, Hyun Jae, Lee, Jung Cheul, Chung, Jin Hong, Song, Si Youn, Yoon, Seok-Keun, Baek, Suk-Hwan
Format: Online
Language:English
Published: Korean Academy of Medical Sciences 2002
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3054965/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3054965/

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