Sebaceous carcinoma of the eyelids: frequent expression of c-erbB-2 oncoprotein.
Ocular sebaceous carcinoma (OSC) is an uncommon malignancy with a potential to recur and metastasize. Some characteristics of sebaceous carcinoma, such as female preponderance, shown in the present series during 11-year period at Korea Cancer Center Hospital, led us to study their hormone receptors...
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Korean Academy of Medical Sciences
2000
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3054683/ |
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pubmed-3054683 |
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pubmed-30546832011-03-15 Sebaceous carcinoma of the eyelids: frequent expression of c-erbB-2 oncoprotein. Cho, K. J. Khang, S. K. Koh, J. S. Chung, J. H. Lee, S. S. Research Article Ocular sebaceous carcinoma (OSC) is an uncommon malignancy with a potential to recur and metastasize. Some characteristics of sebaceous carcinoma, such as female preponderance, shown in the present series during 11-year period at Korea Cancer Center Hospital, led us to study their hormone receptors and c-erbB-2 expression. c-erbB-2 overexpression was very common (83%) in OSC, and was not associated with pathologic findings or clinical outcome. Interestingly, estrogen and progesterone receptor was detected in 4 and 2 cases, respectively, suggesting a role of hormonal influence on this neoplasm. Immunohistochemical and clinicopathologic features of 18 cases of OSC in Korea are presented. Korean Academy of Medical Sciences 2000-10 /pmc/articles/PMC3054683/ /pubmed/11068992 Text en |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Cho, K. J. Khang, S. K. Koh, J. S. Chung, J. H. Lee, S. S. |
| spellingShingle |
Cho, K. J. Khang, S. K. Koh, J. S. Chung, J. H. Lee, S. S. Sebaceous carcinoma of the eyelids: frequent expression of c-erbB-2 oncoprotein. |
| author_facet |
Cho, K. J. Khang, S. K. Koh, J. S. Chung, J. H. Lee, S. S. |
| author_sort |
Cho, K. J. |
| title |
Sebaceous carcinoma of the eyelids: frequent expression of c-erbB-2 oncoprotein. |
| title_short |
Sebaceous carcinoma of the eyelids: frequent expression of c-erbB-2 oncoprotein. |
| title_full |
Sebaceous carcinoma of the eyelids: frequent expression of c-erbB-2 oncoprotein. |
| title_fullStr |
Sebaceous carcinoma of the eyelids: frequent expression of c-erbB-2 oncoprotein. |
| title_full_unstemmed |
Sebaceous carcinoma of the eyelids: frequent expression of c-erbB-2 oncoprotein. |
| title_sort |
sebaceous carcinoma of the eyelids: frequent expression of c-erbb-2 oncoprotein. |
| description |
Ocular sebaceous carcinoma (OSC) is an uncommon malignancy with a potential to recur and metastasize. Some characteristics of sebaceous carcinoma, such as female preponderance, shown in the present series during 11-year period at Korea Cancer Center Hospital, led us to study their hormone receptors and c-erbB-2 expression. c-erbB-2 overexpression was very common (83%) in OSC, and was not associated with pathologic findings or clinical outcome. Interestingly, estrogen and progesterone receptor was detected in 4 and 2 cases, respectively, suggesting a role of hormonal influence on this neoplasm. Immunohistochemical and clinicopathologic features of 18 cases of OSC in Korea are presented. |
| publisher |
Korean Academy of Medical Sciences |
| publishDate |
2000 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3054683/ |
| _version_ |
1611444867245801472 |