Dehydroepiandrosterone-dependent induction of peroxisomal proliferation can be reduced by aspartyl esterification without attenuation of inhibitory bone loss in ovariectomy animal model.
The purpose of this study was to determine whether esterification of dehydroepiandrosterone with aspartate (DHEA-aspartate) could reduce peroxisomal proliferation induced by DHEA itself, without loss of antiosteoporotic activity. Female Sprague-Dawley rats were ovariectomized, then DHEA or DHEA-aspa...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Korean Academy of Medical Sciences
2000
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3054677/ |