Altered remodeling of nucleolar machineries in cultured hepatocytes treated with thioacetamide.
Thioacetamide (TA) is converted into a hyperacetylating agent which causes hepatic necrosis, regeneration, cirrhosis and cancerous transformation. One of the most characteristic toxicities of TA in rat is observed with a 50 mg/kg per day which induces nucleolar enlargement different from that in reg...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Korean Academy of Medical Sciences
2001
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3054557/ |