p21 expression and mutation in gastric carcinoma: analysis by immunohistochemistry and PCR-SSCP.
p21 protein has been reported to be a critical downstream effector of p53 and a potent inhibitor of cyclin-dependent kinases. Thus, the p21 gene is thought to play a central role in tumor suppression. In this study we investigated p21 protein expression and mutation in gastric adenocarcinoma. A tota...
| Main Authors: | , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Korean Academy of Medical Sciences
1998
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3054511/ |