DNA-mediated immunization of mice with plasmid encoding HBs antigen.

In order to develop an experimental DNA vaccine for the prevention and treatment of hepatitis B virus infection, hepatitis B virus surface antigen (HBsAg) DNA was subcloned into an E. coli-eukaryotic cell shuttle vector and was expressed in the Baculovirus expression system. Intramuscular, intraderm...

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Bibliographic Details
Main Authors: Yoon, S. J., Park, J. W., Ahn, S. Y., Choe, B. K., Suh, M. H.
Format: Online
Language:English
Published: Korean Academy of Medical Sciences 1999
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3054368/