TDP-43 Potentiates Alpha-synuclein Toxicity to Dopaminergic Neurons in Transgenic Mice
TDP-43 and α-synuclein are two disease proteins involved in a wide range of neurodegenerative diseases. While TDP-43 proteinopathy is considered a pathologic hallmark of sporadic amyotrophic lateral sclerosis and frontotemporal lobe degeneration, α-synuclein is a major component of Lewy body charact...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Ivyspring International Publisher
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053535/ |