Chinese Ischemic Stroke Subclassification
Accurate classification of stroke has significant impact on patient care and conduction of stroke clinical trials. The current systems such as TOAST, SSS-TOAST, Korean TOAST, and A–S–C–O have limitations. With the advent of new imaging technology, there is a need to have a more accurate stroke subcl...
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| Format: | Online |
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Frontiers Research Foundation
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052771/ |
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pubmed-30527712011-03-22 Chinese Ischemic Stroke Subclassification Gao, S. Wang, Y. J. Xu, A. D. Li, Y. S. Wang, D. Z. Neuroscience Accurate classification of stroke has significant impact on patient care and conduction of stroke clinical trials. The current systems such as TOAST, SSS-TOAST, Korean TOAST, and A–S–C–O have limitations. With the advent of new imaging technology, there is a need to have a more accurate stroke subclassification system. Chinese ischemic stroke subclassification (CISS) system is a new two step system aims at the etiology and then underlying mechanism of a stroke. The first step classify stroke into five categories: large artery atherosclerosis (LAA), including atherosclerosis of aortic arch and intra-/extracranial large arteries, cardiogenic stroke, penetrating artery disease, other etiology, and undetermined etiology. The second step is to further classify the underlying mechanism of ischemic stroke from the intracranial and extracranial LAA into the parent artery (plaque or thrombosis) occluding penetrating artery, artery-to-artery embolism, hypoperfusion/impaired emboli clearance, and multiple mechanisms. Although clinical validation of CISS is being planned, CISS is an innovative system that offers much more detailed information on the pathophysiology of a stroke. Frontiers Research Foundation 2011-02-15 /pmc/articles/PMC3052771/ /pubmed/21427797 http://dx.doi.org/10.3389/fneur.2011.00006 Text en Copyright © 2011 Gao, Wang, Xu, Li and Wang. http://www.frontiersin.org/licenseagreement This is an open-access article subject to an exclusive license agreement between the authors and Frontiers Media SA, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are credited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Gao, S. Wang, Y. J. Xu, A. D. Li, Y. S. Wang, D. Z. |
| spellingShingle |
Gao, S. Wang, Y. J. Xu, A. D. Li, Y. S. Wang, D. Z. Chinese Ischemic Stroke Subclassification |
| author_facet |
Gao, S. Wang, Y. J. Xu, A. D. Li, Y. S. Wang, D. Z. |
| author_sort |
Gao, S. |
| title |
Chinese Ischemic Stroke Subclassification |
| title_short |
Chinese Ischemic Stroke Subclassification |
| title_full |
Chinese Ischemic Stroke Subclassification |
| title_fullStr |
Chinese Ischemic Stroke Subclassification |
| title_full_unstemmed |
Chinese Ischemic Stroke Subclassification |
| title_sort |
chinese ischemic stroke subclassification |
| description |
Accurate classification of stroke has significant impact on patient care and conduction of stroke clinical trials. The current systems such as TOAST, SSS-TOAST, Korean TOAST, and A–S–C–O have limitations. With the advent of new imaging technology, there is a need to have a more accurate stroke subclassification system. Chinese ischemic stroke subclassification (CISS) system is a new two step system aims at the etiology and then underlying mechanism of a stroke. The first step classify stroke into five categories: large artery atherosclerosis (LAA), including atherosclerosis of aortic arch and intra-/extracranial large arteries, cardiogenic stroke, penetrating artery disease, other etiology, and undetermined etiology. The second step is to further classify the underlying mechanism of ischemic stroke from the intracranial and extracranial LAA into the parent artery (plaque or thrombosis) occluding penetrating artery, artery-to-artery embolism, hypoperfusion/impaired emboli clearance, and multiple mechanisms. Although clinical validation of CISS is being planned, CISS is an innovative system that offers much more detailed information on the pathophysiology of a stroke. |
| publisher |
Frontiers Research Foundation |
| publishDate |
2011 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052771/ |
| _version_ |
1611444133830852608 |