Mass Spectrometry Analysis of Hepcidin Peptides in Experimental Mouse Models

The mouse is a valuable model for unravelling the role of hepcidin in iron homeostasis, however, such studies still report hepcidin mRNA levels as a surrogate marker for bioactive hepcidin in its pivotal function to block ferroportin-mediated iron transport. Here, we aimed to assess bioactive mouse...

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Bibliographic Details
Main Authors: Tjalsma, Harold, Laarakkers, Coby M. M., van Swelm, Rachel P. L., Theurl, Milan, Theurl, Igor, Kemna, Erwin H., van der Burgt, Yuri E. M., Venselaar, Hanka, Dutilh, Bas E., Russel, Frans G. M., Weiss, Günter, Masereeuw, Rosalinde, Fleming, Robert E., Swinkels, Dorine W.
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050808/