High dose concentration administration of ascorbic acid inhibits tumor growth in BALB/C mice implanted with sarcoma 180 cancer cells via the restriction of angiogenesis

To test the carcinostatic effects of ascorbic acid, we challenged the mice of seven experimental groups with 1.7 × 10-4 mol high dose concentration ascorbic acid after intraperitoneal administrating them with sarcoma S-180 cells. The survival rate was increased by 20% in the group that received high...

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Main Authors: Yeom, Chang-Hwan, Lee, Gunsup, Park, Jin-Hee, Yu, Jaelim, Park, Seyeon, Yi, Sang-Yeop, Lee, Hye Ree, Hong, Young Seon, Yang, Joosung, Lee, Sukchan
Format: Online
Language:English
Published: BioMed Central 2009
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732919/