PRMT5 is required for cell-cycle progression and p53 tumor suppressor function

Protein arginine methyltransferases (PRMTs) mediate the transfer of methyl groups to arginines in proteins involved in signal transduction, transcriptional regulation and RNA processing. Tumor suppressor p53 coordinates crucial cellular processes, including cell-cycle arrest and DNA repair, in respo...

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Bibliographic Details
Main Authors: Scoumanne, A., Zhang, J., Chen, X.
Format: Online
Language:English
Published: Oxford University Press 2009
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731901/