Lysosomal localization of GLUT8 in the testis – the EXXXLL motif of GLUT8 is sufficient for its intracellular sorting via AP1- and AP2-mediated interaction

Lysosomal localization of GLUT8 in the testis – the EXXXLL motif of GLUT8 is sufficient for its intracellular sorting via AP1- and AP2-mediated interaction

The class III sugar transport facilitator GLUT8 co-localizes with the lysosomal protein LAMP1 in heterologous expression systems. GLUT8 carries a [D/E]XXXL[L/I]-type dileucine sorting signal that has been postulated to retain the protein in an endosomal/lysosomal compartment via interactions with cl...

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Bibliographic Details
Main Authors: Diril, Muhammed Kasim, Schmidt, Stefan, Krauß, Michael, Gawlik, Verena, Joost, Hans-Georg, Schürmann, Annette, Haucke, Volker, Augustin, Robert
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2009
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730553/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730553/

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