Mycobacterium tuberculosis evades macrophage defenses by inhibiting plasma membrane repair
Induction of macrophage necrosis is an important strategy used by virulent Mycobacterium tuberculosis (Mtb) to avoid innate host defense. In contrast, attenuated Mtb causes apoptosis, which limits bacterial replication and promotes T cell cross priming by antigen presenting cells. Here we demonstrat...
| Main Authors: | , , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
2009
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730354/ |