New Alzheimer Amyloid β Responsive Genes Identified in Human Neuroblastoma Cells by Hierarchical Clustering

Alzheimer's disease (AD) is characterized by neuronal degeneration and cell loss. Aβ42, in contrast to Aβ40, is thought to be the pathogenic form triggering the pathological cascade in AD. In order to unravel overall gene regulation we monitored the transcriptomic responses to increased or decr...

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Bibliographic Details
Main Authors: Uhrig, Markus, Ittrich, Carina, Wiedmann, Verena, Knyazev, Yuri, Weninger, Annette, Riemenschneider, Matthias, Hartmann, Tobias
Format: Online
Language:English
Published: Public Library of Science 2009
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727959/