Small molecule tyrosine kinase inhibitors in pancreatic cancer

Pancreatic cancer has proven to be chemo-resistant, with gemcitabine being the only cytotoxic agent approved for advanced pancreatic cancer since 1996. Tyrosine kinase inhibitors represent a newer generation of chemotherapeutic agents targeting specific tumor pathways associated with carcinogenesis...

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Bibliographic Details
Main Authors: Gupta, Sachin, El-Rayes, Bassel F
Format: Online
Language:English
Published: Dove Medical Press 2008
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727890/