Pitfalls, prevention, and treatment of hyperuricemia during tumor lysis syndrome in the era of rasburicase (recombinant urate oxidase)

Along with hydration and urinary alkalinization, allopurinol has been the standard agent for the management of hyperuricemia in patients with a high tumor burden at risk of tumor lysis syndrome; however, this agent often fails to prevent and treat this complication effectively. Rasburicase (recombin...

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Bibliographic Details
Main Authors: Pession, Andrea, Melchionda, Fraia, Castellini, Claudia
Format: Online
Language:English
Published: Dove Medical Press 2008
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727789/